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Binding affinity
Binding affinity
induces proinflammatory responses Engulfment of apoptotic cells by microvascular endothelial cells
Hematology / Microcirculation / Cell Adhesion / Apoptosis / Cell line / Humans / Endothelial Cells / Blood / Clinical Sciences / Apoptose / Phagocytosis / Endothelial cell / Necrosis / Leukocytes / Binding affinity / Humans / Endothelial Cells / Blood / Clinical Sciences / Apoptose / Phagocytosis / Endothelial cell / Necrosis / Leukocytes / Binding affinity
DNA repair efficiency in transgenic mice over expressing ribosomal protein S3
Oxidative Stress / DNA damage / DNA repair / Transgenic Mice / Protein synthesis / Humans / Mutation / Mice / Female / Animals / Male / Ribosomal proteins / Oxidative Damage / In Vitro Studies / Oxidative Dna Damage / Ribosomal Protein / Binding affinity / Humans / Mutation / Mice / Female / Animals / Male / Ribosomal proteins / Oxidative Damage / In Vitro Studies / Oxidative Dna Damage / Ribosomal Protein / Binding affinity
A Direct Comparison of Anti-microRNA Oligonucleotide Potency
Micro Rna / MicroRNA / Comparative Study / Gene Silencing / RNA interference / miRNA / Humans / Low Dose / Mice / Pharmaceutical / Animals / Male / Plasmids / High Pressure Liquid Chromatography / microRNAs / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / HeLa cells / Transfection / LNA / Antisense drug / Base Sequence / Potency / Chemical Modification / Oligonucleotide / Binding affinity / Ribonucleases / miRNA / Humans / Low Dose / Mice / Pharmaceutical / Animals / Male / Plasmids / High Pressure Liquid Chromatography / microRNAs / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / HeLa cells / Transfection / LNA / Antisense drug / Base Sequence / Potency / Chemical Modification / Oligonucleotide / Binding affinity / Ribonucleases
A Direct Comparison of Anti-microRNA Oligonucleotide Potency
Micro Rna / MicroRNA / Comparative Study / Gene Silencing / RNA interference / miRNA / Humans / Low Dose / Mice / Pharmaceutical / Animals / Male / Plasmids / High Pressure Liquid Chromatography / microRNAs / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / HeLa cells / Transfection / LNA / Antisense drug / Base Sequence / Potency / Chemical Modification / Oligonucleotide / Binding affinity / Ribonucleases / miRNA / Humans / Low Dose / Mice / Pharmaceutical / Animals / Male / Plasmids / High Pressure Liquid Chromatography / microRNAs / Liquid Chromatography / Electrospray Ionization Mass Spectrometry / HeLa cells / Transfection / LNA / Antisense drug / Base Sequence / Potency / Chemical Modification / Oligonucleotide / Binding affinity / Ribonucleases
215. Investigating Urokinase Plasminogen Activator Receptor (CD87), as a Potential Target for Non-Viral Gene Transfer
Pharmacology / Technology / Biological Sciences / Cell line / Molecular Targeted Therapy / Gene Transfer / Binding affinity / Gene Transfer / Binding affinity
A novel Phytochrome B allele in Arabidopsis thaliana exhibits partial mutant phenotype: a short deletion in N-terminal extension reduces Phytochrome B activity
Plant Biology / Arabidopsis thaliana / Red Light / Plant Growth Regulation / Codon Usage / White Light / Amino Acid Profile / Binding affinity / White Light / Amino Acid Profile / Binding affinity
Quick and simple synthesis of 11C-(+)-α- dihydrotetrabenazine to be used as a pet radioligand of vesicular monoamine transporters | Síntesis rápida y simplificada de 11C-(+)-α- dihidrotetrabenazina para su utilización como radioligando PET de los transportadores vesiculares de monoaminas
Positron Emission Tomography / Binding affinity
Quick and simple synthesis of 11C-(+)-α- dihydrotetrabenazine to be used as a pet radioligand of vesicular monoamine transporters | Síntesis rápida y simplificada de 11C-(+)-α- dihidrotetrabenazina para su utilización como radioligando PET de los transportadores vesiculares de monoaminas
Positron Emission Tomography / Binding affinity
8-amino-6-(arylsulphonyl)-5-nitroquinolines: novel nonpeptide neuropeptide Y1 receptor antagonists
Organic Chemistry / Bioorganic and medicinal Chemistry / Binding affinity
Comparison of Dipeptidyl Peptidase IV Resistance and Biological Activities in Vitro and in Vivo
Biological activity / Binding affinity
A proximal tryptophan in NO synthase controls activity by a novel mechanism
Inorganic Chemistry / Kinetics / Cytochrome C / Spectrophotometry / Tryptophan / Heme / Enzyme / Steady state / Hydrogen Bond / Hydrogen Bonding / Nitric Oxide Synthase / Cysteine / Molecular Conformation / Protein Conformation / Inorganic Biochemistry / Amino Acid Substitution Rates / Recombinant Proteins / Site-directed Mutagenesis / Binding affinity / Heme / Enzyme / Steady state / Hydrogen Bond / Hydrogen Bonding / Nitric Oxide Synthase / Cysteine / Molecular Conformation / Protein Conformation / Inorganic Biochemistry / Amino Acid Substitution Rates / Recombinant Proteins / Site-directed Mutagenesis / Binding affinity
3,4-Diamino-2,5-thiadiazole-1-oxides as potent CXCR2/CXCR1 antagonists
Organic Chemistry / Kinetics / Pharmacokinetics / Peroxidase / Cell line / In Vitro / Humans / Animals / Neutrophils / Rats / Rat / Bioorganic and medicinal Chemistry / Oxides / Structure activity Relationship / Chemical Synthesis / Interleukin / Binding affinity / In Vitro / Humans / Animals / Neutrophils / Rats / Rat / Bioorganic and medicinal Chemistry / Oxides / Structure activity Relationship / Chemical Synthesis / Interleukin / Binding affinity
Fluoroalkyl α side chain containing 3,4-diamino-cyclobutenediones as potent and orally bioavailable CXCR2–CXCR1 dual antagonists
Organic Chemistry / Animals / Rats / Protein Binding / Binding affinity
Probing RNA-protein interactions using pyrene-labeled oligodeoxynucleotides: Qβ replicase efficiently binds small RNAs by recognizing pyrimidine residues
Molecular Biology / RNA / Fluorescent Dyes and Reagents / Fluorescence Lifetime / Proteins / Small RNA / Real Time / Steady state / Fluorescence anisotropy / Base Sequence / RNA Dependent RNA Polymerase / Fluorometry / Binding Site / Nucleic Acid Conformation / Dissociation Constant / DNA probes / Biochemistry and cell biology / Molecular Structure / Nucleic Acid / Titrimetry / single stranded DNA / Binding affinity / Molecular Sequence Data / Small RNA / Real Time / Steady state / Fluorescence anisotropy / Base Sequence / RNA Dependent RNA Polymerase / Fluorometry / Binding Site / Nucleic Acid Conformation / Dissociation Constant / DNA probes / Biochemistry and cell biology / Molecular Structure / Nucleic Acid / Titrimetry / single stranded DNA / Binding affinity / Molecular Sequence Data
A novel serotonin transporter ligand: (5-Iodo-2-(2-dimethylaminomethylphenoxy)-benzyl alcohol
Brain Imaging / Metabolism / Positron Emission Tomography / DISTRIBUTION / Serotonin / Dopamine / Brain / Iodine / Animals / Serotonin Transporter / Male / Central Nervous System / Rat Brain / Membrane transport proteins / Clinical Sciences / Hydrogen Peroxide / Rats / Single Photon Emission Computed Tomography / Rat / Swine / Positron / Distribution / Radiopharmaceuticals / Chemical Synthesis / Ligands / Binding Site / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor / Binding affinity / Dopamine / Brain / Iodine / Animals / Serotonin Transporter / Male / Central Nervous System / Rat Brain / Membrane transport proteins / Clinical Sciences / Hydrogen Peroxide / Rats / Single Photon Emission Computed Tomography / Rat / Swine / Positron / Distribution / Radiopharmaceuticals / Chemical Synthesis / Ligands / Binding Site / Serotonin Uptake Inhibitors / Selective serotonin reuptake inhibitor / Binding affinity
TNFalpha Primes Polymorphonuclear Leukocytes for an Enhanced Respiratory Burst to a Similar Extent As Bacterial Lipopolysaccharide
Lipopolysaccharide / Antibodies / Humans / Clinical Sciences / Neutrophils / Lipopolysaccharides / Tumor necrosis factor-alpha / Cell Surface Markers / Oxygen Consumption / Immunoglobulin / Respiratory Burst / Binding affinity / Lipopolysaccharides / Tumor necrosis factor-alpha / Cell Surface Markers / Oxygen Consumption / Immunoglobulin / Respiratory Burst / Binding affinity
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